Biotics &
Microbiome
Health
Gut microbiota plays a crucial role in different functions in the body. These discoveries have opened exciting perspectives in the prevention and treatment of numerous health conditions.
get the science of expertsThe impact of Biotics for Microbiome Health
The discovery of the impact of human intestinal microbiota on health and well-being is constantly evolving. The collective genome of the intestinal microbiota, termed microbiome, is estimated to contain at least 100 times more genes than our own genome (Qin et al., 2010).
Certain microbiota components can have beneficial effects, therefore modulating the microbiome towards a healthier composition has received more and more scientific interests, especially in the early-life period where the microbiota is progressively established, which leaves more rooms for modulation. Strategies of antenatal and early-life intestinal microbiome modulation are the most effective approaches to promote a resilient, diverse, and healthy microbiota, which has the greatest long-term potential to benefit health (the programming effect).
Probiotics, prebiotics, synbiotics, and more recently postbiotics – all these “biotics” have the potential to modulate the intestinal microbiome but acting differently. The Food and Agriculture Organization of the United Nations and the WHO (FAO/WHO) defines probiotic as “live microorganisms which when administered in adequate amounts confer a health benefit on the host” (Hills et al., 2014). Several probiotic strains have been identified, tested safe for use in infants and conferring health benefits in diverse areas. More research is needed to uncover new probiotic strains and/or on new health benefits.
Experts Interviews on biotics & microbiome health
Experts Interviews - Bioactive proteins in human milk : benefits of OPN (Osteopontin)
Prof. Bo Lonnerdal
Biotics & Microbiome Health
Osteopontin (OPN) is a glycoprotein, that is found in body tissues including bone and body fluids such as human milk. It plays an important role in immune, brain and gut development in early life. In this expert interview, Prof. Bö Lonnerdal, leader of a world-renowned research program in paediatric nutrition at the University of California, responds to important questions relating to Osteopontin’s mechanisms of action and the health benefits associated with it.
Bo Lönnerdal is a Professor of nutrition and medicine at UC Davis, in California. He is the founder of the International Society for Research in Human Milk and Lactation (ISRHML). His scientific research and studies focus on bioactive components in human milk and their underlying mechanisms, such as their contribution to protecting against infection.Prof. Lönnerdal has published more than 600 scientific articles. He is a member of the American Society of Nutrition (ASN) and the European Society for Research on Human Milk and lactation (ISRHML). As an Expert in early life nutrition, he has been part of the editorial board of several journals and in several Experts Panels for the World Health Organization (WHO).
experts publications on biotics & microbiome health
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Probiotics maintain intestinal secretory immunoglobulin A levels in healthy formula-fed infants: a randomised, double-blind, placebo-controlled study
Biotics & Microbiome Health
L. Xiao et al. (2019)
As timely probiotic administration was suggested to promote immune system development in formula-fed infants, this study aimed at assessing the safety and the effects of a probiotic supplement on mucosal immune competence and digestive function in formula-fed infants.
Precision Nutrition and the Microbiome, Part I: Current State of the Science
Biotics & Microbiome Health
S. Mills et al. (2019)
The gut microbiota is a highly complex community which evolves and adapts to its host over a lifetime. It has been described as a virtual organ owing to the myriad of functions it performs, including the production of bioactive metabolites, regulation of immunity, energy homeostasis and protection against pathogens.
Webinars on biotics & microbiome Health
Webinar - The role of Osteopontin in Infant Health
Prof. Bo Lönnerdal
Biotics & Microbiome Health
Osteopontin (OPN) is a glycoprotein, that is found in body tissues including bone and body fluids such as human milk. It plays an important role in immune, brain and gut development in early life. In this webinar, Professor Bö Lonnerdal, leader of a world-renowned research program in pediatric nutrition at the University of California, gives an in-depth presentation on Osteopontin’s mechanisms of action and the health benefits associated with it.
Bo Lönnerdal is a Professor of nutrition and medicine at UC Davis, in California. He is the founder of the International Society for Research in Human Milk and Lactation (ISRHML). His scientific research and studies focus on bioactive components in human milk and their underlying mechanisms, such as their contribution to protecting against infection. Prof. Lönnerdal has published more than 600 scientific articles. He is a member of the American Society of Nutrition (ASN) and the European Society for Research on Human Milk and lactation (ISRHML). As an Expert in early life nutrition, he has been part of the editorial board of several journals and in several Experts Panels for the World Health Organization (WHO).
Funded projects on biotics & microbiome health
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Elucidating mother-infant and bacterial factors related to the early acquisition and intestinal colonization of infants by E. coli and AIEC
Biotics & Microbiome Health
Simpson K., Cornell University, USA, 2022
Mechanistically, inflammatory bowel diseases (IBD), principally Crohn’s disease (CD) and ulcerative colitis (UC), are considered a consequence of dysregulated interplay between host genetic-susceptibility and immunity, the enteric microenvironment, and environmental “triggers”, but the specific interactions that lead to IBD are unresolved.
PROTECT: Priming for healthy eating via the diet-microbiota -gut-brain axis
Mother & Child Health & Nutrition
Schellekens H., University College Cork, Ireland, 2021
Diet remains one of the main drivers of the obesity pandemic, in particular the overconsumption of calorically dense palatable foods in early life. There is increasing interest to further our understanding of the pathways in the brain that drive excess unhealthy food consumption and how they are established from the onset.
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4 areas of expertise
Stay at the forefront of healthcare innovation and best practices, empowering yourself with the latest research and insights in our four areas of expertise : mother and child health, biotics and microbiome health, immunity and allergy and brain development.
Resources Information for parents
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