Immunity
& Allergy

Infants’ allergies have dramatically increased in recent years and currently affect 20% of the population. Studies have shown that nutrition and microbiota development in early life can impact their development.

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Food
Allergies & atopic diseases

Food allergy is one the of the most common chronic diseases of childhood, especially if persistent, impacting growth and nutrition, quality of life, and may even be life threatening due to the risk of anaphylaxis. Cow’s milk allergy (CMA) is one of the most common types of food allergy in industrialised countries (Flom and Sicherer 2019).

Dietary management of CMA consists of 2 approaches, one is “passive” approach, consisting of elimination diet, the other one is “proactive” approach, meaning actively modulate the immune system. Gut microbiota dysbiosis induces altered gut function, which results in aberrant immune response towards allergic pathways instead of protective tolerogenic pathways (Plunkett and Nagler 2017).

Furthermore, the gut immune system, the so-called gut-associated lymphoid tissue (GALT), has 70 – 80% of the immune cells of the body (Castro and Arntzen, 1993), which make it the largest ‘immune organ” of the body. Targeting gut microbiota by using nutritional factors to actively immunomodulate the immune system opens therefore exciting research potential.

Experts Interviews on immunity & allergy

Experts Interviews - Atopic dermatitis

Prof. Jean-Pierre Chouraqui

Immunity & Allergy

Atopic dermatitis, often characterised by atopic eczema, is one of the most common inflammatory skin diseases worldwide, with approximately 230 million people around the world affected by it.Atopic dermatitis (AD) usually starts in infancy, and affects up to 20% of children. The symptoms of atopic dermatitis in infants are usually skin dryness and itchiness.In this expert’s interview, Dr. Chouraqui, explains the causes, the various diagnosis, and the clinical features of atopic dermatitis.

Dr. Jean-Pierre Chouraqui is a member of the French Society of Paediatrics (SFP) and of Paediatric Gastroenterology Hepatology and Nutrition (GFHGNP).Besides conducting several Clinical studies, he is the author and co-author of more than 140 scientific articles and reviews and gave speeches at more than 250 national and international congresses. His main clinical research focus is on infant nutrition, and particularly, the effect of probiotics on infants’ health, food allergies, and gastrointestinal disorders.

experts publications on immunity & Allergy

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Webinars on Immunity & Allergy

Webinar - Cow's milk allergy

Prof. Christophe Dupont

Immunity & Allergy

Cow’s milk allergy is a common diagnosis in early life. It consists of an allergic reaction to the protein present in cow’s milk and manifests as a variety of symptoms such as skin reactions and digestive issues which commonly develop in infants. In this webinar, Prof. Christophe Dupont, from the University of Paris Descartes, addresses the clinical symptoms and the treatments for this condition.

Dr. Christophe Dupont has been a Paediatric Gastroenterologist (GI) since 1980, and has specialised in endoscopy, with a focus on endoscopy in neonates and allergic children. He was formerly head of the ambulatory paediatric GI department at Hospital Necker in Paris and Emeritus professor at Paris-Descartes University. Dr. Dupont is now president of the Committee of Nutrition of the French Society of Pediatrics and he is currently working in the field of pediatric GI and severe food allergy, diagnosis and treatment. He is also the co-founder of the company DBV Technologies. He is the principal investigator in numerous clinical trials, in the field of gastroesophageal reflux, diarrhea, constipation, infant nutrition and food allergy. Dr. Dupont has published over 300 publications in peer-reviewed papers.

Funded projects on immunity & Allergy

4 areas of expertise

Stay at the forefront of healthcare innovation and best practices, empowering yourself with the latest research and insights in our four  areas  of expertise : mother and child health, biotics and microbiome health, immunity and allergy and brain development.

Resources Information for parents

Raising awareness of maternal and infant health to parents is an important duty of health care professionals. We created the parents corner to provide you with insightful resources to help you in your mission.

parents corner